Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats

A.S. Idoko; S. Umar; G.O. Adejo; N.U. Imam; A. S. Zaharaddeen; Z. S. Abubakar and 
A. Abdullahi

doi:10.4314/njbas.v30i2.23

E-ISSN 2756-4843 | ISSN 0794-5698

2022, Vol: 30, Issue: 2

30 / 2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Original Research

Nig. J. Basic Appl. Sci.. 2022; 30(2): 178-183

doi: 10.4314/njbas.v30i2.23

Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats

A.S. Idoko, S. Umar, G.O. Adejo, N.U. Imam, A. S. Zaharaddeen, Z. S. Abubakar and A. Abdullahi.

Abstract
Industrial and environmental activities continuously release chemicals such as 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD) that are hazardous to human health. This research seeks to assess the potentials of Allium cepa and Curcuma longa in suppressing 2,3,7,8-tetracholorodibenzo-p-dioxintoxicity. Forty (40) male Wistar rats weighing 121.77±16.23 g were divided into eight groups of five (5) rats per group. Positive control was fed standard diet, and given 2 µg/kg/week of TCDD in 0.5ml DMSO while normal control was fed standard diet and given 0.5ml dimethyl sulfoxide (DMSO)/kg body weight/week instead of TCDD. Other groups received 2µg/kg/week of TCDD in 0.5ml DMSO and were fed varied inclusion levels of powdered Allium cepa and Curcuma longa. On the 35th day of the experimental period, the rats were sacrificed and serum prepared from collected blood for antioxidant enzymes, malondialdehyde (MDA) and lipid profile determinations. All treated groups had significantly (p<0.05) higher activities of antioxidant enzymes when compared with the positive control. Malondialdehyde concentration was significantly (p<0.05) lower in the treated groups than the positive control (187.87±5.65 nmol/l). Lipid profiles were significantly improved upon by the inclusion of Allium cepa and Curcuma longa. Therefore, we conclude that dyslipidaemia and oxidative stress due to exposure to dioxin in rats could be suppressed by consumption of 2.5% to 5%inclusion levels of powdered onion and/or turmeric in the diet.

Key words: ,3,7,8-tetracholorodibenzo-p-dioxin; glutathione peroxidase; glutathione reductase; malondialdehyde; Allium cepa; Curcuma longa.

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by A.S. Idoko Articles by S. Umar Articles by G.O. Adejo Articles by N.U. Imam Articles by A. S. Zaharaddeen Articles by Z. S. Abubakar and A. Abdullahi
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Idoko A, Umar S, Adejo G, Imam N, Zaharaddeen AS, . Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. Nig. J. Basic Appl. Sci.. 2022; 30(2): 178-183. doi:10.4314/njbas.v30i2.23

Web Style

Idoko A, Umar S, Adejo G, Imam N, Zaharaddeen AS, . Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. https://www.njbas-udus.com/?mno=45384 [Access: February 02, 2023]. doi:10.4314/njbas.v30i2.23

AMA (American Medical Association) Style

Idoko A, Umar S, Adejo G, Imam N, Zaharaddeen AS, . Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. Nig. J. Basic Appl. Sci.. 2022; 30(2): 178-183. doi:10.4314/njbas.v30i2.23

Vancouver/ICMJE Style

Idoko A, Umar S, Adejo G, Imam N, Zaharaddeen AS, . Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. Nig. J. Basic Appl. Sci.. (2022), [cited February 02, 2023]; 30(2): 178-183. doi:10.4314/njbas.v30i2.23

Harvard Style

Idoko, A., Umar, . S., Adejo, . G., Imam, . N., Zaharaddeen, . A. S. & (2022) Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. Nig. J. Basic Appl. Sci., 30 (2), 178-183. doi:10.4314/njbas.v30i2.23

Turabian Style

Idoko, A.S., S. Umar, G.O. Adejo, N.U. Imam, A. S. Zaharaddeen, and Z. S. Abubakar and A. Abdullahi. 2022. Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. Nigerian Journal of Basic and Applied Sciences, 30 (2), 178-183. doi:10.4314/njbas.v30i2.23

Chicago Style

Idoko, A.S., S. Umar, G.O. Adejo, N.U. Imam, A. S. Zaharaddeen, and Z. S. Abubakar and A. Abdullahi. "Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats." Nigerian Journal of Basic and Applied Sciences 30 (2022), 178-183. doi:10.4314/njbas.v30i2.23

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Idoko, A., Umar, . S., Adejo, . G., Imam, . N., Zaharaddeen, . A. S. & (2022) Fortification of diets with Curcuma longa and Allium cepa ameliorates dioxin-induced dyslipideamia and oxidative stress in Wistar rats. Nigerian Journal of Basic and Applied Sciences, 30 (2), 178-183. doi:10.4314/njbas.v30i2.23

Most Viewed Articles

Isolation and Identification of Fungi Associated with the Spoilage of Sweet Orange (Citrus Sinensis) Fruits In Sokoto State
I.Y. Tafinta, K.Shehu, H. Abdulganiyyu, A.M. Rabe and A. Usman
Nig. J. Basic Appl. Sci.. 2013; 21(3): 193-196
» Abstract & References

Heavy Metals and Physicochemical Properties of Soils in Kano Urban Agricultural Lands
U.M. Dawaki, A.U. Dikko, S.S. Noma and U. Aliyu
Nig. J. Basic Appl. Sci.. 2013; 21(3): 239-246
» Abstract & References

Study on Biochemical Indices of Liver Function Tests of Albino Rats Supplemented with Three Sources of Vegetable Oils [English]
K.E. Imafidon and L.O. Okunrobo
Nig. J. Basic Appl. Sci.. 2012; 20(2): 105-110
» Abstract

Effect of Sources of Organic Manure on Growth and Yields of Okra (Abelmoschus esculentus L.) in Sokoto, Nigeria [English]
R.A. Tiamiyu, H.G. Ahmed and A.S. Muhammad
Nig. J. Basic Appl. Sci.. 2012; 20(3): 213-216
» Abstract

Optimum Temperature and Thermal Stability of Crude Polyphenol Oxidase from some Common Fruits
AB Bello, MS Sule
Nig. J. Basic Appl. Sci.. 2012; 20(1): 27-31
» Abstract

Most Downloaded

The Swelling Behaviour of Polystyrene (PS)/ Polyvinylacetate (Pvac) Blends in Different Solvents and the Effects of -Cellulose used as Filler on the Electrical Conductivity. [English]
P. A. P. Mamza and B.T. Nwufo
Nig. J. Basic Appl. Sci.. 2008; 16(2): 165 -
» Abstract

Characterization and Classification of Soils on an Agricultural landscape in Dingyadi District, Sokoto State, Nigeria
M.B. Sharu, M. Yakubu, S.S. Noma and A.I.Tsafe
Nig. J. Basic Appl. Sci.. 2013; 21(2): 137 -147
» Abstract

Optimization of Steam Distillation of Essential Oil of Eucalyptus tereticornis by Response Surface Methodology [English]
M.S. Galadima, A.S. Ahmed, A.S. Olawale and I. M. Bugaje
Nig. J. Basic Appl. Sci.. 2012; 20(4): 368-372
» Abstract

Biogas production through Co-digestion of palm oil mill effluent with cow manure
Umar Hayatu Sidik, Firdausi Bin Razali, Sharifah Rafidah Wan Alwi, Fadimtu Maigari
Nig. J. Basic Appl. Sci.. 2013; 21(1): 79-84
» Abstract

Most Cited Articles

Microwave Assisted Biodiesel Production From Lagenaria Vulgaris Seed Oil Using Amberlyst 15 Ion Exchange Resin and Eggshell as Catalysts
A. Umar, A. Uba, M. L. Mohammed, M. N. Almustapha, C. Muhammad, J. Sani
Nig. J. Basic Appl. Sci.. 2018; 26(2): 88-96
» Abstract » doi: 10.4314/njbas.v26i2.13
Cited : 1 time [Click to see citing article]

Copyright of Published Articles

Published articles in the Nigerian Journal of Basic and Applied Sciences (NJBAS) are subject to the copyright laws of the Usmanu Danfodiyo University governing intellectual property rights. Authors retain the copyright to their articles published by NJBAS provided the original source of the publication is properly acknowledged. The University reserves the right however, to retract any work published by NJBAS provided there is sufficient evidence to inform such decision. These rights are subject to change without notice from or liability to Nigerian Journal of Basic and Applied Sciences.

Copyright � 2023 Nigerian Journal of Basic and Applied Sciences All Rights Reserved. Subject to change without notice from or liability to Nigerian Journal of Basic and Applied Sciences.
For best results, please use Internet Explorer or Google Chrome

Contact Information

Nigerian Journal of Basic and Applied Sciences (NJBAS)

Usmanu Danfodiyo University, Sokoto

P.M.B. 2346, Sokoto, Nigeria

email: njbas@udusok.edu.ng; publicationeditor.njbas@udusok.edu.ng

Prof. A. A. Aliero

Editor-in-Chief

+2348034635146

Dr. M. L. Mohammed

Publication Editor

+2348032303517

Dr. M. E. Sadiq

Managing Editor

+2349091113143; ;

POLICIES & JOURNAL LINKS

Contact Information

How to cite this article